1984 Volume 32 Issue Supplement2 Pages 10-19
The antibiotic activities of TA-058 were examined against 1, 119 strains isolated clinically from the year 1981 to 1982 including two species of Streptococci, two Staphylococci, five Enterobacteriaceae, six Pseudomonas, two Acinetobacter, one Achromobacter, Flavobacterium and B. fragilis in comparison with other penicillins. Antimicrobial activities against B. fragilis were compared with cephems.
TA-058 showed more active antimicrobial activities or at least similar activities to SBPC in most of the strains tested. But antimicrobial activities of TA-058 were inferior to those of PIPC and MZPC against many of the strains tested. Resistant strains which show more than 100μg/ml of minimum inhibitory concentrations were observed in all strains except for S. agalactiae and P. putrefaciens.