ASSAY METHODS OF TA-058 CONCENTRATIONS IN BODY FLUIDS
II. HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC ASSAY METHOD
1984 Volume 32 Issue Supplement2 Pages 112-118
Details
1984 Volume 32 Issue Supplement2 Pages 112-118
The High-Performance Liquid Chromatographic (HPLC) assay method for the quantitative determination of TA-058 in body fluids and the stability in human bile were described.
The chromatographic separation of TA-058 and body fluids blank was good. The recovery rates of added TA-058 from those body fluids were 96-103%.
The concentration of TA-058 in human serum, urine and bile detected by HPLC methods were in good agreement with those obtained by the Microbiological method.
TA-058 was stable in human bile during 7 days when it was kept in frozen state at-20°C.
