1984 Volume 32 Issue Supplement2 Pages 359-362
Clinical effectiveness of TA-058, a new semisynthetic penicillin, was studied in 9 adult cases of infectious diseases. These cases consisted of 8 cases of acute and chronic upper or lower respiratory tract infections and 1 case of urinary tract infection TA-058 was given to the patients with dosage of 1-2 g/day intravenously. Clinical effectiveness was determined about 7 days later. Clinical and bacteriological effectiveness were obtained in 5 out of 7 cases (71.4 %). Excellent efficacy was obtained in 4 cases, good in one case and poor in two cases respectively. There were no serious adverse reactions.
It was concluded that TA-058 was supposed to be active and useful antibiotic against respiratory infections by gram-negative bacteria without major side effects.
