CLINICAL STUDIES ON AC-1370
1984 Volume 32 Issue Supplement9 Pages 285-290
Details
1984 Volume 32 Issue Supplement9 Pages 285-290
AC-1370, a new parenteral cephalosporin, was evaluated clinically for 12 patients (15 cases) aged 36-77 years with respiratory tract infection (4 cases) and with urinary tract infection (11 cases). A daily dose of AC-1370 was 1-2 g by intravenous injection twice a day and duration of AC-1370 therapy was for 5 to 9 days.
The results were as follows.
1. The clinical response to AC-1370 therapy of respiratory tract infection was good in 2 cases, fair in one case, and poor in one case, and that of urinary tract infection was excellent in 2 cases, good in 4 cases, and fair in 2 cases.
The efficacy rate was 67%.
2. In the laboratory data, abnormal elevation of serum Al-P, as a side effect, was observed in one case after the administration of AC-1370.
