CLINICAL STUDIES ON AC-1370 TREATMENT FOR SURGICAL INFECTIONS
1984 Volume 32 Issue Supplement9 Pages 493-497
Details
1984 Volume 32 Issue Supplement9 Pages 493-497
AC-1370 was studied in 10 cases with surgical infections (urinary tract infection 3, intraperitoneal abscess 2, periproctal abscess 1, perityphlic abscess 1, wound infection 1, cholangitis 1, acute peritonitis 1) and administered 1 g twice a day for 5 days.
The results were good in 7 cases, poor in 3 cases with effective rate 70%.
Bacterial effects with 16 strains in 10 species were as follows: 3 strains of B. fragilis, 2 strains of P. morganii, each one strain of E. coli, S. pyogenes, S. epidermidis were eradicated and each one strain of E. coli and S. pyogenes decreased but each one strain of P. morganii, Enterobacter, P. putida, Serratia, P. inconstans, S. faecalis persisted.
No side effects were observed, and in laboratory findings, no abnormal elevations of transaminase, BUN and creatinine were found.
