Abstract
Clinical effect of sultamicillin, a mutual prodrug consisting of ampicillin and sulbactam, was studied in 35 patients with uncomplicated urinary tract infection and in 9 patients with complicated urinary tract infection.
Sultamicillin was orally administered at a dose of 375mg three times a day, or 750mg twice a day. Clinical effects of Sultamicillin on patients with uncomplicated urinary tract infection were excellent in 27 cases, moderate in 8 cases, and overall effectiveness rate was 100%. On patients with complicated urinary tract infection, clinical effects were excellent in 2 cases, moderate in 6 cases, poor in 1 case and overall clinical effectiveness rate was 89%.
During the treatment with Sultamicillin, diarrhea and loose stool were observed in 1 case each, but they were weak enough to continue the treatment.
