CLINICAL EFFECTIVENESS OF SUPPRESSIVE TREATMENT WITH NORFLOXACIN IN COMPLICATED URINARY TRACT INFECTIONS

Abstract

NFLX 200 mg 3 times a day for 7 to 14 days was administered as initial treatment to patients with complicated UTI without indwelling catheter.Subsequently, patients in whom NFLX treatment was not effective were excluded from the current study.The remainder, who were evaluated as excellent or moderate, were randomly divided into 2 groups. In the first group, NFLX 200 mg was administered as an evening dose for the prevention of infection. Patients in the second group were not given any drug (controls).
The recurrence rates of the NFLX and the control groups after 4 weeks were 2.9% and 41.7%, respectively.Of the treated patients, 11 received the treatment more than 10 weeks, and in these the recurrence rate was 9%(1/11).