7432-S IN UROLOGY
1989 Volume 37 Issue Supplement1 Pages 499-512
Details
1989 Volume 37 Issue Supplement1 Pages 499-512
We used 7432-S in the treatment of urinary tract infections (UTI) to investigate its clinical efficacy and safety. The subjects were: 5 patients with acute uncomplicated cystitis, 47 with chronic complicated UTI, and one with urethritis.
The following results were obtained.
1) Clinical efficacy was evaluated according to the criteria of the Japanese UTI Committee.
The overall efficacy was 100% in 4 patients with acute uncomplicated cystitis. In 46 patients with chronic complicated UTI, it was excellent in 30, moderate in 6 and poor in 10, the overall efficacy rate being 78%.
2) Bacteriologically, 3 of 4 strains (75%) were eradicated in acute uncomplicated cystitis and 49 of 57 strains (86%) in chronic complicated UTI.
3) Clinical response was fair in one patient with urethritis.
4) As to side-effects, rash of the extremities was observed in one patient, but no abnormal laboratory findings.
