1990 Volume 38 Issue 5 Pages 484-488
A six year-old girl with complicated cyanotic heart disease and asplenia was affected by a brain abscess of the right temporal lobe. She was successfully treated with surgical aspiration followed by drainage and intravenous administration of imipenem/cilastatin sodium for five weeks.
The offending pathogen isolated from the abscess was microaerophilic Streptococcus, for which the MIC of imipenem was 0.01μg/ml.
We think it worthwhile to give imipenem/cilastatin sodium in the treatment of the central nervous system infections, including brain abscesses.