Abstract
Cefpirome (CPR), a new parenteral cephalosporin, was administered to 6 patients with gynecological and obstetric infections by i.v. drip infusion at a dose of 0.5-1 g twice daily for 7-13 days. Diagnosis were salpingitis in two patients, and retroperitoneal abscess, Douglas' abscess, pyosalpinx and pyometra in one patient each.
Clinical efficacy was good in all patients, the efficacy rate being 100%, and the bacteriological effect was eliminated in 2, exchanged in 1 and unknown in 3.
No remarkable side effects were found. Regarding laboratory values, slight elevation of GOT and GPT was found in two cases, and leukopenia in one case.
From the above results, we consider CPR to be a useful agent for obstetric and gynecological infections.
