Multicenter study of FK 037 in chronic respiratory infection
1994 Volume 42 Issue 10 Pages 1162-1175
Details
1994 Volume 42 Issue 10 Pages 1162-1175
A multicenter open study was conducted to evaluate the clinical efficacy, safety and optimal effective dosage of FK 037 in chronic respiratory tract infections.
1. The total number of patients enrolled was 55, 3 of whom were judged to be “unkown” in the assessment of clinical efficacy.
2. The clinical efficacy in 52 patients was judged to be “excellent” in 14 and “good” in 34 an efficacy rate of 92.3%. The efficacy rates according to dosage were 90.0% at 0.5g×2/day, 93.1% at 1.0g×2/day and 92.3% at 2.0g×2/day.
3. The bacteriological effects in 31 patients were “eradicated” in 26, “decreased” in 3 and “unchanged” in 2, for an eradication rate of 83.9%.
4. As side effects, a small papule was observed in 1 patient, and abnormal laboratory findings were observed in 7 patients.
From the above results, we concluded that 1.0g×2/day of FK 037 was useful in chronic respiratory tract infections.
