1994 Volume 42 Issue Supplement4 Pages 792-794
Biapenem (BIPM), new carbapenem antibiotic, was administered to 5 patients with bacterial pneumonia. The clinical efficacy was excellent in 1 case, good in 3 cases and unknown in 1 case. Causative organisms were detected in 2 strains of 2 species (Pseudomonas aeruginosa, Streptococcus pneumoniae), were eradicated.
No adverse reaction was observed, though two patients showed abnormal laboratory findings during the treatment: elevation of OPT, γ-GTP, LAP in I case, elevation of GOT, OPT, Al-P, γ-GTP in 1 case.
These results suggest that BIPM is useful in the treatment of bacterial pneumonia.