Biapenem in urinary tract infections
Keywords:
Biapenem
1994 Volume 42 Issue Supplement4 Pages 814-819
Details
1994 Volume 42 Issue Supplement4 Pages 814-819
Biapenem (BIPM) was administered to 14 patients with urinary tract infections (UTI) and 2 patients with acute uncomplicated pyelonephritis and one patient with acute prostatitis at a daily dosage of 600mg b.i.d. for 3-5 days, and its clinical efficacy and safety were evaluated. The following results were observed:
1) Clinical efficacy was evaluated according of the criteria of the Japanese UTI Committee. The overall efficacy rate was 70% in the 10 patients with chronic complicated UTI.
2) Bacteriologically, 18 (90%) of 20 strains were eradicated in chronic complicated UTI.
3) As for side effects, eruption occurred in one patient. Abnormal laboratory findings were transient elevation of GOT, GPT, γ-GTP, ALP, LAP and LDH in one patient.
From the above results, we consider that BIPM is a useful and safe antibiotic for UTI.
