Abstract
We evaluated the clinical efficacy and safety of cefluprenam (CFLP), a new injectable cephem antibiotic, at a dose of 1.0 g twice daily for 4-15 days in 7 patients with bacterial pneumonia.The clinical efficacy was excellent in 1 patient, good in 5 and poor in 1. Streptococcus pneumoniae were isolated from 3 patients, and all strains were eradicated after CFLP administration. Two cases of skin rash were observed, and a mild elevation of GOT and GPT was observed in 1 case.