Abstract
A newly developed oral macrolide antibacterial agent, azithromycin (AZM), was administered to 2 cases of acute bronchitis, 1 of pneumonia and 1 of diffuse panbronchiolitis during the acute aggravation period, to examine its clinical effect and possible adverse reactions. The drug was administered at a dose of 250 or 500mg once a day for 1-3 days. The response was rated good in all 4 cases. As adverse reactions due to the administration of AZM, diarrhea appeared in 1 case. No abnormal laboratory values thought to be related to the administered drug were observed.