1997 Volume 45 Issue 3 Pages 148-154
BO-2727 New Formulation, a new injectable carbapenem antibiotic, was administered to 24 patients with complicated urinary tract infections (UTI). Of the 24 patients, 21 were assessed according to the criteria proposed by the Japanese UTI Committee. The overall clinical efficacy rate was 76.2%(excellent response in 7 patients, moderate in 9 and poor in 5). Bacteriologicaly, 28 (90.3%) of 31 strains isolated were eradicated. As for side effects, loose stools were observed in one patient; an increase in basophilic leukocytes, in one patient; and liver function test abnormalities, in 3 patients.