Antimicrobial susceptibility of Gram-negative bacillus causing late-onset neonatal bacteremia in a neonatal intensive care unit

Abstract

Between 1998 and 2004, we studied the minimal inhibitory concentration (MICs) of 11 strains of Gramnegative bacilli isolated from blood in patients with late-onset neonatal bacteremia in a neonatal intensive care unit. Pathogenic organisms were 3 in Acinetobacter spp., 2 in Enterobacter cloacae, 2 in Ralstonia pidcettii, and 1 each in Klebsiella pneumoniae, Burkhokleria cepacia, Pseudomonas aeruginosa, and Proteus mirabilis.
The susceptibility of ciprofloxacin, imipenem, and meropenem to these organisms exceeded 80%. Ciprofloxacin was not susceptible to P. aeruginosa, and imipenem and meropenem were not susceptible to R pickettii.