Correlation Diagrams of Stereoisograms for Cyclobutane Stereoisomers

Abstract

Correlation diagrams of stereoisograms are proposed to discuss stereoisomerism of cyclobutane derivatives. An RS-stereoisomeric group for characterizing a cyclobutane skeleton is defined by starting from the point group D4h so that the global symmetry of each cyclobutane derivative is characterized to be its subgroup. Then, the corresponding stereoisogram is drawn. A tetrahedral promolecule for characterizing the local symmetry at each RS-stereogenic center is derived to belong to a subgroup of an RS-stereoisomeric group due to the point group Td. Then, the corresponding stereoisogram is drawn. Relationships between these stereoisograms are discussed by constructing the correlation diagram of stereoisograms.