Abstract
Congenital constriction band anomalies are a constellation of malformations associated with annular groove, amputation, and syndactyly. We report a case of constriction band anomalies with bilateral cleft lip and palate. The patient had syndactyly of upper limbs and amputation of a lower limb with cleft lip and palate at birth. At one month, the child was referred to Niigata University Medical and Dental Hospital for cleft lip and palate. A Hotz plate was set for nursing at two months. Multiple surgical procedures were subsequently performed during the initial 8 years and 3 months, including cheiloplasty, palatoplasty and alveolar bone graft for cleft lip and palate. In addition, orthopedic surgical procedures for limbs were performed to improve their deformity. Orthodontic treatment has been performed since the patient was 12 years old.
Constriction band anomalies are a rare condition in which it is hypothesized that a fibrous band of amniotic tissue results in variable soft tissue derangements. Other terms that have been used to describe this condition are amniotic band syndrome and amnion rupture sequence. These have been used to describe the fact that the patient may present with craniofacial, thoracic, abdominal, and/or limb involvement. In this report, we discuss the relationship between constriction band anomalies and cleft lip and palate from the viewpoint of their etiology. The mechanical effect of the amniotic band may inhibit fusion of prominences for organogenesis of the lip or palate in the fetus.
