Clinicostatistical Analysis of Cleft Lip and/or Palate

—Associated Congenital Anomalies—

Abstract

A clinico-statistical analysis of associated congenital anomalies was made on 661 patients with cleft lip and/or palate, who were examined at our department from January 1967 to December 2011. The following results were obtained:
1. The number of patients with other associated congenital anomalies and/or syndrome was 82, which was a 12.4% incidence rate.
2. Of the associated congenital anomalies，congenital heart disease was observed in 27 cases (4.1%), anomalies of extremities in 18 cases (2.7%), auricular anomalies in 17 cases (2.6%), and anomalies of eyes and palpebral conjunctiva in 12 cases (1.8%).
3. In the patients with associated congenital anomalies, the number of associated congenital anomalies in a patient averaged 1.3 with a maximum of 6.
4. Of 30 cases (4.5%)were diagnosed as a syndrome, Pierre Robin syndrome was observed in 17 cases and the first and second branchial arch syndrome and Treacher Collins syndrome in 2.