Abstract
A clinicostatistical investigation was carried out on patients with cleft lip and/or palate in the Clinics for Maxillo-Oral Disorders, Tohoku University Hospital during the 20-year period from 1995 through 2014, and the following results were obtained.
1. The total number of patients with cleft lip and/or palate was 1,428. The overall male to female ratio was 1 : 0.93.
2. Regarding area of residence, 65.4% of patients were from Sendai city and Miyagi prefecture, a proportion which has increased in recent years.
3. The distribution of cleft type was as follows: cleft lip and palate 40.0%, cleft lip and alveolus 30.0%, cleft palate 30.0%. Cleft lip and palate was more common in males than in females (P<0.01). Cleft palate was more common in females than in males (P<0.01).
4. The peak age of the first visit was 0 years. The mean age of the first visit was 3 years, 11 months.
5. The total number of primary patients with cleft lip and/or palate was 897 (male: 475, female: 422). The overall male to female ratio was 1 : 0.89. Regarding area of residence, 74.2% of primary patients were from Sendai city and Miyagi prefecture. Primary cleft lip and palate was more common in males than in females (P<0.01). Primary cleft palate was more common in females than in males (P<0.01). The mean age of the first visit in primary cases was 6 months.
6. The number of patients with other associated congenital anomalies was 182, which was an incidence rate of 20.3%.
