Statistical Observation of Cleft Lip Alveolus and Palate in the Department of PRS, Kawasaki Medical School Hospital during the Past 10 Years from 1978 to 1987.

Abstract

A clinico-statistical review of 462 patients with cleft lip alveolus and palate who had recieved a primary operation during the past 10 years from January 1978 to December 1987 was carried out.
The following findings were noted.
1. The geographic distribution of the patients enrolled in this review was 41.2 % from Okayama prefecture and 27.3 % from Hiroshima prefecture.
2. The cleft morphology was classified as follows: cleft lip in 72 cases (15.6 %), cleft lip alveolus in 98 cases (21.1 %), cleft lip and palate in 6 cases (1.3 %), cleft lip alveolus and palate in 186 cases (40.3 %), cleft palate in 100 cases (21.6 %).
3. All types of clefts were more frequently observed in males than in females.
4. Unilateral clefts were significantly predominant as compared with bilateral ones, and the incidence of left side cleft was significantly higher than that of the right side.
5. A familial disposition was found in 39 of the 462 families examined. (8.4%).
6. The incidence of cleft-associated malformations was 16.7 %, with a high percentage for cleft palate alone. These malformations were most commonly associated with abnormalities of the limbs; e. g. Pierre-Robin syndrome and auricular malformation.