Abstract
Abstract: We experience clinically associated anomalies with cleft lip & cleft palate most often. The incidence of associated anomalies has been reported in many monographs. The percentage from 2 to 3% at the lowest and approximately over 30% at the highest is reported. It is considered that definite percentage cannot be obtained because newborns and fetuses for treatment are subjected, and the standard for anomalies is not established. In total,1,267 patients with cleft lip, cleft palate, cleft lip & palate who were in our hospital from January,1980 to December,1990. At this time, we investigated and totaled the associated anomalies in not only external epidermises but also in internal organs which were recognized during diagnosis or surgery.
The following results were obtained.
1. The associated anomalies with the skull, face, trunk, extremities and internal organ system including mental retardation was observed in 353 patients, and observed in 27.9% overall. This percentage was comparatively high so far as we investigated.
2. The associated anomalies were observed in the order of cleft palate, cleft lip & palate, and cleft lip, and the same order as all previous reports.
3. Among the associated anomalies, congenital heart disease was most often observed, followed by mental retardation, Pierre-Robin syndrome, umbilical hernia, ear malformation, extremity malformation, hydrocele testis, and inguinal hernia.
