Abstract
A clinico-statistical investigation was carried out on 472 patients with cleft lip and palate who had undergone a primary operation at the Department of Oral Surgery, Faculty of Medicine, University of Ryukyus during the 15 year period from September,1973 to August,1988.
1. There were 264 males and 208 females, with a male to female ratio of 1.3:1.
2. Cleft morphology was classified as follows: cleft lip only and/or alveolus in 139 cases (29.4 %), cleft lip and palate and/or alveolus in 218 cases (46.2 %), and cleft palate only in 115 cases (24.4 %).
3. Unilateral cleft lip and/or alveolus and palate were seen in 263 cases, and bilateral condition in 94 cases, with a ratio of 2.8: 1. In the 263 cases, the ratio for affected side was illustrated as 1: 1.9(right: left).
4. It was found that 12.4 % of 451 patients had a birth weight of 2500 or less grams. It was also found that 3.0 % of 466 mothers were aged 40 or older at subject's birth.
5. Other congenital anomalies were found to be associated in 6 0 cases (13.0 %), congenital heart disease were seen in 23 cases (5.0 %).
6. Familial occurence was found in 123 of 455 families of the propositi (27.0 %).
