Abstract
Cornelia de Lange syndrome (CDLS) is characterized by characteristic faces, multiple congenital malformations, and mental retardation. In the oral region, micrognathia and high arched palate were found in most cases and 20-30 % of the cases were associated with cleft palate.
Two cases of CDLS's cleft palate surgery, which we experienced recently, were reported.
One case was a 3-year 7-month-old female (BW: 6,700 g) and the other was a 13-year-old female (BW: 19,900 g). Both children had no language development, but cleft palate closure was performed the push back method under general anesthesia. The timing for the operation was recommended after conference with pediatricians and anesthetists. There were no complications in terms of perioperative management. After the cleft palate operation, because of mental retardation, no improvement was found in language development. However both children seemed to have a good appetite without food impaction in the palate or to the nasal cavity.
