Abstract
S incet he establishmenot f this clinica t MiyazakiM edicalC ollegei n 1978, t here have been 441 cases of cleft lip and/or palate. Among them,312 primary cases were analyzed statistically.
The result were as follows:
1. The total number of prim ary cases during the past 19 years was 312, and the mean was 12.9 ger year.
2. Clef t morphology was classified into four categories, cleft lip and/or alveolus (CL) in 90 cases (28.8 %), cleft lip and palate and/or alveolus (CLP) in 81 cases (26.0 %), cleft palate only (CPO) in 111 cases (35.6 %), and submucous cleft palate (SMCP) in 30 cases (9.6 %). CPO cases were most frequently observed.
3. The laterality in CL and CL P cases was unilateral in 78.4 % and bilateral 21.6 %. Left laterality (1.7: 1) was noted in unilatereral cases.
4. The mean age of mothers at delivery w as similar to the normal group.
5. In CL and CLP cases,53.3 % and 63.0 % of those were referred b y obstetricians respectively, and 38.8 % of CPO and 46.7 % of SMCP were referred by pediatricians due to speech problem.
6. CL and/or CP were also found in 22 families representing 7.1 % of total propositi.
7. Associated congenital anomalies were found in 26.4 % of all cases, and th ey were more frequently found in CP and SMCP.
