Clinical Neuropsychopharmacology and Therapeutics
Online ISSN : 1884-8826
ISSN-L : 1884-8826
Case Report
Hypoglycemia with atypical antipsychotics, but not with typical antipsychotics: A case report
Shinichiro OchiMasao AbeHideaki ShimizuJun-ichi IgaShu-ichi Ueno
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2020 Volume 11 Pages 5-8


Atypical antipsychotics cause hypoglycemia as a rare metabolic adverse effect in patients without diabetes. However, its mechanism is not sufficiently clarified. In the present case, a patient with schizophrenia presented with hypoglycemia induced by risperidone and olanzapine after becoming generally debilitated, but not by haloperidol. A complex interaction of serotonergic and adrenergic pathways with atypical antipsychotics may play a role in hypoglycemia. When prescribing atypical antipsychotics for patients, clinicians should be careful not only about the amount and character of the antipsychotics, but also the general status of the patients.

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© 2020 The Japanese Society of Clinical Neuropsychopharmacology
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