Abstract
A short term multicenter study on evaluation of the usefulness, acceptability and tolerability of Genotropin KabiQuick (GKQ) was carried out in 36 patients with classical growth hormone (GH) deficiency. Of 36 patients or their parents, 32 (88.9%) evaluated GKQ as superior in preparative procedure to the conventional injection syringe system. Thirty (83.3%) including all of the 6 self-injection patients evaluated that dosing with GKQ was easier. Thirty-two (88.9%) said that GKQ could be handled in a more sanitary condition. Twenty-six (72.2%) felt that the handling of GKQ was easier. The average time needed for each injection with GKQ was 4.0±3.2 min. which was significantly shorter than that with the conventional system (7.8±6.2 min). Ten, twelve and thirteen patients complained that GKQ gave more, equal and less pain respectively. Nineteen (52.8%) commented that the plunger of GKQ was hard to push. Twenty-two (61.1%) preferred GKQ and 5 (13.9%) reverted to the conventional system for future treatment. Doctors concerned with this study assessed that GKQ was useful in 27 patients (75%), but not useful in 2 patients (5.6%). It is concluded that GKQ is an easy handling device which provides quick, safe and sterile daily injections for patients or parents, but an easily movable plunger, a smaller size device and a lower dose-system GKQ are requested for further improvement.