低温状態におけるタンパク質モデル化合物の疎水性相互作用に関する研究

吉村 幸浩; 竹清 貴浩; 渡邊 真佑子; 岡本 知カ羅

doi:10.20585/cryobolcryotechnol.57.1_51

Study on the Hydrophobic Interaction of a Protein Model Compound at Low Temperature

Yukihiro YOSHIMURA, Takahiro TAKEKIYO, Mayuko WATANABE, Chikara OKAMOTO

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Keywords: Hydration structure, Hydrophobic interaction, Protein model compound, Guanidine hydrochloride, Raman spectroscopy

JOURNAL FREE ACCESS

2011 Volume 57 Issue 1 Pages 51-54

DOI https://doi.org/10.20585/cryobolcryotechnol.57.1_51

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Abstract

We have investigated the effect of guanidine hydrochloride (GdnHCl) on the hydration structure of 1-butyl-3-methylimidazolium chloride ([bmim][Cl]) used as a protein model compound. It was found that the addition of GdnHCl induces the change in the hydration structure of [bmim][Cl]. Our results indicate that the interaction between water molecules and GdnHCl is an important factor for the protein denaturation.

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