Cytological Studies of Tumors, XXVI

Chromosome analysis of a human mammary carcinoma

Abstract

The present paper describes the results of a chromosomal analysis in tumor cells of a human mammary carcinoma. The material for study was derived by centrifuging from the pleural fluid from a patient. It was established that there is present at least a stemline of tumor cells which are characterized by a hypertriploid complex of chromosomes, primarily contributing to the neoplastic growth. A possible item of evidence has been presented that there may be an additional existence of tumor stem-cells with a hyperhexaploid complex.