Abstract
Chromosome number and karyotypes of the Misima subline of hyperdiploid Ehrlich tumor and three single cell clones derived from that subline were examined. The stemline cells of the Misima subline were characterized by the modal chromosome number of 44 including one A-chromosome (telocentric with secondary constriction), two B-chromosomes (large metacentrics), one Sa-chromosomes (chromosome with short arm) and two or three minutes. One small metacentric chromosome was remarkable, especially as it appeared after the 61 st transplant generation. The three clones had almost the same karyotypes as those of the stemline of the parental cell population. Karyotypes of the Misima subline and clones were compared with those of other authors and the differences between them were discussed.