Further Data on the Common Origin of Various Stem-Lines in Human Tumors

Abstract

Cytogenetic findings in a malignant effusion of ovarial origin are presented. Karyotype analysis revealed the existence of several cell lines. The relationship between these lines has been established by the study of the marker chromosomes; the cells belonging to the minor lines arose by polyploidization from the major line cells. These data support the concept of the single cell origin of various cell lines in human tumors.