Suppression Effect of CIPC on Nucleoli in Vicia faba Root Tip Cells

Abstract

The effects of CIPC, or isopropyl N-(3-chlorophenyl) carbamate, on nucleolar activity of Vicia faba root tip cells were examined. The nucleoli of CIPC-treated cells were smaller, frequetly had segregated contents, much lower RNA contents, and reduced biosynthesis of RNA by two-thirds.
These facts are discussed in conjunction with the hypothesis that the mode of action of CIPC is somehow related to inhibition of gene derepression at the molecular level.