Strain Difference in the Phenotype of Radiation-InducedThymic Lymphoma in DBA1 and NFS Mice

Abstract

We investigated the phenotype of thymic lymphoma induced by fractionated wholebody X-irradiation in DBA1 and NFS mice using mAbs for different cell surface antigens and flow cytometry. The results demonstrated that there was distinct differences in the phenotype of lymphoma between DBA1 and NFS mice, and that the lymphomas developed in NFS mice were more phenotypically mature than those from DBA1 mice.