The curent status on bisphenol A and its related compounds

Abstract

 Bisphenol A (BPA; 2,2-bis(4-hydroxyphenyl)propane) of 500,000 tons manufactures or it is imported in Japan. And about 90 percent of BPA is used as a synthetic raw material of the polycarbonate resin and epoxy resin.
 The manufacture and sales of polycarbonate nursing bottles and dinnerware have been almost completely discontinued in Japan ever since the endocrine disruption effect became a national matter of concern, and the Japanese Can Manufacturers Association's guideline specifies the bisphenol A elution level as 0.005 μg/mL or lower in canned drinks and 0.01 μg/mL or lower in general canned food for metal cans manufactured in Japan. Therefore the bisphenol A exposure level in Japan has been reduced dramatically compared to that of 10 years ago. It is even lower than those in the U.S. or Europe. The number of compounds that the structure is similar to BPA (BPA relevant compound) increases on the other hand every year.
 In addition to the current state of the restriction of BPA and the exposure situation, the ecological effects of BPA and BPA relevant compounds were reviewed.