Abstract
The application of adenovirus (Ad) vectors, which are widely used in gene therapy, depends on CAR (coxsackievirus and adenovirus receptor) expression on the cells. To overcome this problem, the capsid proteins of Ad vectors have been genetically modified. Here, we introduce several types of capsid-modified Ad vectors. Furthermore, we describe the application of capsid-modified Ad vectors into some kinds of stem cells for regenerative medicine.