Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Polymer chemistry for DDS” Editor : Masayuki Yokoyama
Photoresponsive polymeric materials for drug delivery systems
double targeting with photoresponsive polymers
Takeshi Nagasaki
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JOURNAL FREE ACCESS

2008 Volume 23 Issue 6 Pages 637-643

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Abstract
Photoresponsive polymeric materials are promising not only for cell-targeting in vivo, but also for intracellular navigations such as the internalization, the endosomal escape, and the nuclear import. Furthermore, the controlled release as well as the activation of drugs is caused by the photoresponsive delivery. Finally, such photoresponsive polymeric system can pave the way for double targeting of drugs resulting in temporal and spatial delivery. The photoresponsive synchronization of biocompatible materials and novel photo-irradiating apparatus might bring a various happiness to the refractory patients in near future.
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© 2008 Japan Society of Drug Delivery System
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