Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Pulmonary drug delivery with microparticles” Editor : Hirokazu Okamoto
Nanotechnologies in development of pulmonary drug delivery
Kohsaku KawakamiShaoling Zhang
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JOURNAL FREE ACCESS

2009 Volume 24 Issue 5 Pages 477-483

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Abstract
Various nanotechnologies have been utilized in recent researches on pulmonary drug delivery. Notably, pulmonary administration of nanoparticulate formulation is regarded as promising in terms of effective deposition and prolonged retention of the drugs.
In this review, recent development of the nanotechnology-driven particle engineering for pulmonary drug delivery, with emphasis on control of surface characteristics of the particles using nanofabrication technique. Also noticed is the electrospray method, which is a novel technology to prepare nanoparticles. The advantage of this method is that it can be operated in ambient temperature and pressure conditions.
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© 2009 Japan Society of Drug Delivery System
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