Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Frontiers of innovative drug discovery based on breakthrough DDS technology” Editor : Hideyoshi Harashima
Innate immunity and next-generation vaccine
Taiki AoshiKen Ishii
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JOURNAL FREE ACCESS

2012 Volume 27 Issue 1 Pages 19-27

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Abstract
Recent proceedings in the research of molecular mechanism of innate immune system enable us to design and construct more safe and effective vaccine based on the scientific rationale instead of empirical way. We describe here an overview of the current understanding of how innate immunity elicit and enhance adaptive immune responses, including CD4T cell differentiation to Th1, Th2, and Th17. We also discuss possible application of drug delivery system for next-generation vaccine development.
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© 2012 Japan Society of Drug Delivery System
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