Abstract
While the development of a new medicine makes little increase, improvement in the efficacy and safety of the existing drug can be achieved by new DDS formation in clinical each subject (respiratory organ, circulatory organ, otolaryngology and infectious disease). The introduction of biomaterial and control of targeting functions is the key to improve the disposition characteristics of a drug in DDS development. On the other hand, revision of the Japanese Pharmacopoeia was performed according to new dosage forms.In this paper, the present condition of the DDS formulation for clinical application was reviewed in clinical each subject and infectious disease. Furthermore, I outlined the basic DDS research supporting the development of new DDS formulation. In particular, I focused on inhalation device, stent, new injection devise and vaccine.
