Intracellular trafficking of excipients and the involvement of transporters in the efflux of excipients

Abstract

For the development of DDS products, excipients attract lots of attention and the appropriate selection and evaluation of excipients are expected. In this review, the author overviews the evaluation of excipients. The author also presents the recent studies concerning the intracellular trafficking processes from intracellular uptake to extracellular efflux of the excipients which are used as drug carrier, and the involvement of transporters in the efflux of excipients from the cells.