Abstract
With an advent of new generation photo-sensitizers including 5-Amino levulinic acid (5-ALA) or its derivatives, photodynamic diagnosis (PDD) or photodynamic therapy (PDT) has been widely applied for the detection of invisible tumor or for the new therapeutic modalities in genito-urinary (GU) malignancies. In particular, PDD-assisted TURBT (transurethral resection of bladder tumor) may contribute to eliminate the heterogeneous outcome after TURBT among institutions by reducing the surviving invisible tumors. Issues of the future would be head-to head comparison of detection ability to other detection modalities including NBI (narrow band imaging), or molecular elucidation of the role of false positivity of PDD.
