2018 Volume 33 Issue 5 Pages 406-413
Current advances in the treatment of inflammatory bowel disease (IBD) are mainly due to improvement in selectivity or specificity of therapeutic target molecules and mechanisms of action. However, it is not necessarily sufficient from the viewpoint of selective target to gastrointestinal tracts. Development of drug delivery system targeted to the gastrointestinal tract using biodegradable microspheres, which could carry and sustained release various materials such as corticosteroids, anti-inflammatory cytokines and growth factors would be expected to contribute to future therapeutic strategy for inflammatory bowel disease.
