Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
[Feature articles] “DDS to deliver innovative medical care to bedside:cancer chemotherapy” Editor:Tetsuya Hamaguchi
Advantages of antibody usage in liposomal DDS for cancer chemotherapy
Kosuke ShimizuNaoto Oku
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JOURNAL FREE ACCESS

2019 Volume 34 Issue 1 Pages 22-28

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Abstract
Liposome is a vesicle composed of a lipid bilayer and widely used as a drug carrier for injectable formulation of drugs and targeting drug delivery system. On the other hand, because an antibody has a potential to strongly and specifically recognize a targeted molecule, it can be said that utilizing the antibody in DDS achieves effective drug delivery to a targeted site such as tumor tissue and ideal medication. In this review, we describe the outline of antibody-modified liposome for active targeting DDS and introduce our recent research on tumor targeting using the antibody-modified liposomes for cancer chemotherapy.
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© 2019 The Japan Society of Drug Delivery System
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