Development and challenges in treatment of autoimmune diseases

Abstract

The treatment of autoimmune diseases has advanced dramatically with the use of biologics, in recent years. JAK inhibitors have shown groundbreaking efficacy as oral medications and several drugs have been approved. The efficacy of these drugs is not limited to rheumatoid arthritis, but they are also effective in treating auto-inflammatory diseases such as inflammatory bowel disease. However, sufficient efficacy has not been observed in treating autoimmune diseases.