Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
 
Worldwide development of lipo-PGE1
Rie IgarashiKeiko HoshiTakahide MatsudaYutaka Mizushima
Author information
JOURNAL FREE ACCESS

2003 Volume 18 Issue 5 Pages 426-430

Details
Abstract
Lipo-PGE1 was introduced onto the Japanese market in 1988 and since then it has been widely used in clinical practice. Today, the preparation became applicable clinically also in Korea and China. PGE1 itself is relatively unstable, and amount of PGE1 will be released from LM. Therefore, we recently produced a new lipo-PGE1, in which a chemically stable PGE1 prodrug (AS013) was incorporated into LM. The new lipo-PGE1 showed an enhanced pharmacological activity, and was stable even at room temperature for 3 years. Now in USA its clinical study is ongoing.
Content from these authors
© Japan Society of Drug Delivery System
Previous article Next article
feedback
Top