Central Neurilemmoma of the Mandible with Rapid Growth : Report of a Case

Abstract

A rare case of central neurilemmoma arising in the mandible is reported. The tumor revealed unusual rapid growth in 2 years. To obtain pathological diagnosis of this tumor, an immunohistochemical technique using antibodies against myelin basic protein and S-100 protein was applied to the biopsy specimen. The immunohistochemical examination revealed the overgrowth of nerve sheath cells. The macroscopic and histological examination of the surgical material confirmed that the tumor was a neurilemmoma. In this report we discuss the usefulness of the immunohistochemical examination in diagnosing neurogenic tumor in a biopsy specimen.