2004 Volume 24 Issue 3 Pages 277-286
This study investigated the clinical results of 251 patients with primary squamous cell carcinoma in the oral cavity to make clear the usefulness and problems of the modality. The patients were treated in the former first Department of Oral and Maxillofacial Surgery, Showa University, School of Dentistry. They were devided into two groups according to the treatment period : the 1st period (-1990) and the 2 nd period (1991-).
The results obtained were as follows.
1. The overall survival rate in the 1 st period was 77.4% at 5 years and 71.8% at 10 years.
The rate in the 2nd period was 79.4% both at 5 and 10 years.
2. The 5-year survival rate of patients with the buccal mucosa, tongue, or the lower gingiva carcinoma was relative high. But the rate of patients with the upper gingival cancer was low.
3. The 5-year survival rate of T2 patients increased in the later period, although the rate decreased in T3 and T4 patients.
4. The survival rate of NO patients increased in the later period, although the rate of N1 and N2 patients decreased.
5. The survival rate of stage II patients increased in the later period, although the rate of Stage I, III, and IV patients decreased.
6. The survival rate of the patients who had undergone only surgery, or operation with chemotherapy had higher survival rate than patients who had been treated with operation, chemotherapy, and radiotherapy.
These results suggested that new treatment modality should be intensively developed for patients with advanced squamous cell carcinoma to upgrade their prognosis. It is also necessary to train talented persons with enough technique and knowledge.
