Abstract
A 72-year-old woman developed red papules and annular erythematous plaques on her trunk and limbs. A histological analysis of an annular plaque revealed a necrobiotic central mass of collagen in the dermis which was surrounded by inflammatory lymphocytes and foreign-body giant cells. Laboratory examination revealed pancytopenia. Based on these findings, a diagnosis of generalized granuloma annulare with aplastic anemia was made. We treated her with bath-PUVA therapy. After 29 treatments (82.8 J/cm2), thelesions completely disappeared, and pancytopenia also improved. Six months later, the same lesions and pancytopenia recurred, They were again improved with 50 more treatments (178.4 J/cm2). Bath-PUVA therapy was highly effective for both the skin lesions and the pancytopenia.
