Skin Eruptions after Eradication Therapy for Helicobacter pylori (HP)

Abstract

Disseminated erythmatous papular, eruptions developed in six patients within one week of completion of eradication therapy for Helicobacter pylori (HP) for peptic ulcer. Two of cases were suspected to be amoxicillin-induced drug eruption. Five of them had been treated with hypotensive drugs. The relationship between the three drugs used in HP eradication and hypotensive drugs should be considered in terms of the cause of the eruption. As eradication therapy for HP increases, cases with eruptions may also increase. Therefore, careful observation is mandatory for patients under going eradication therapy for HP, especially those being treatecl with hypotensive drugs.